Comparison of urinary aflatoxin M1 and aflatoxin albumin adducts as biomarkers for assessing aflatoxin exposure in Tanzanian children
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چکیده
منابع مشابه
Efficient Conjugation of Aflatoxin M1 With Bovine Serum Albumin through Aflatoxin M1-(O-carboxymethyl) Oxime and Production of Anti-aflatoxin M1 Antibodies
BACKGROUND Aflatoxins are the most extensively studied group of mycotoxins produced by molds, especially the Aspergillus group, which are highly toxic to animals and humans. OBJECTIVES Since immunoassay is a simple and rapid method for the analysis of many toxic substances in comparison to the chromatographic methods, it is necessary to produce specific and sensitive antibodies for detection ...
متن کاملAflatoxin M1 in Milk - FSA4018
Aflatoxins are mycotoxins of major concern to the dairy industry. Most mycotoxins are found in grain, usually grown in a drought, although they may contaminate pasture grass and occasionally hay. Most frequently, aflatoxins are found in corn (see Figures 1-3) and cottonseed, and sometimes in their byproducts, but also on rare occasions in soybeans or distiller’s grain. Peanut products also may ...
متن کاملEvaluation of methods for quantitation of aflatoxin-albumin adducts and their application to human exposure assessment.
Aflatoxin (AF) albumin adducts are found in peripheral blood after exposure to aflatoxin B1 (AFB1) and the measurement of these adducts is potentially a useful tool in the epidemiological study of the role of AFB1 in the etiology of liver cancer. Three complementary approaches to the quantitation of AF-albumin adducts are described: (a) enzyme-linked immunosorbent assay (ELISA) performed direct...
متن کاملEvaluation of Methods for Quantitation of Aflatoxin-Albumin Adducts and Their Application to Human Exposure Assessment1
Aflatoxin (AF) albumin adducts are found in peripheral blood after exposure to aflatoxin B, (AI-H,) and the measurement of these adducts is potentially a useful tool in the epidemiolÃ3gica!study of the role of AFBi in the etiology of liver cancer. Three complementary approaches to the quantitation of AF-albumin adducts are described: (a) enzymelinked immunosorbent assay (ELISA) performed direct...
متن کاملAflatoxin B1 albumin adducts in plasma and aflatoxin M1 in urine are associated with plasma concentrations of vitamins A and E.
BACKGROUND Although aflatoxin exposure has been associated with micronutrient deficiency in animals, there are few investigations on the effects of aflatoxin exposure on micronutrient metabolism in humans. OBJECTIVE To examine the relationship between aflatoxin B1 (AFB1) albumin adducts (AF-ALB) in plasma and the aflatoxin M1 (AFM1) metabolite in urine and plasma concentrations of retinol (vi...
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ژورنال
عنوان ژورنال: Biomarkers
سال: 2017
ISSN: 1354-750X,1366-5804
DOI: 10.1080/1354750x.2017.1285960